WELCOME TO THE DAMANIA LAB!

PUBLICATIONS

PUBLICATIONS

  • 166) Broussard, G, Ni, G, Zhang, Z, Li, Q, Cano, P, Dittmer, DP and Damania B. Barrier-to-autointegration Factor 1 Promotes Gammaherpesvirus Reactivation from Latency. Nature Communications. 2023. (Manuscript in press).

  • 165) Lange, PT and B. Damania. EBV-Positive Lymphomas Exploit Ectonucleotidase Activity to Limit Immune Responses and Prevent Cell Death. mBio. 2023. (Manuscript in press).

  • 164) Damania B, Kenney SC, Raab-Traub N. Epstein-Barr virus: Biology and clinical disease. Cell. 2022 Sep 29;185(20):3652-3670.

  • 163) Zhang H, Wong JP, Ni G, Cano P, Dittmer DP, Damania B. Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency. PLoS Pathog. 2022 Nov 23;18(11):e1010990.

  • 162) White MC, Wu X, Damania B, Oncogenic viruses, cancer biology, and innate immunity. Curr Opin Immunol. 2022 Oct 11;78:102253.

  • 161) Casper C, Corey L, Cohen JI, Damania B, Gershon AA, Kaslow DC, Krug LT, Martin J, Mbulaiteye SM, Mocarski ES, Moore PS, Ogembo JG, Phipps W, Whitby D, Wood C. KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine. NPJ Vaccines. 2022 Sep 20;7(1):108.

  • 160) Huang N, Groover D, Damania B, Moody C. Apoptotic caspases suppress an MDA5-driven IFN response during productive replication of human papillomavirus type 31. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2200206119.

  • 159) Rivera-Soto R, Yu Y, Dittmer DP, Damania B. Combined Inhibition of Akt and mTOR Is Effective Against Non-Hodgkin Lymphomas. Front Oncol. 2021 Jun 18;11:670275

  • 158) Lange PT, White MC, Damania B. Activation and Evasion of Innate Immunity by Gammaherpesviruses.

    J Mol Biol. 2021 Aug 23:167214.

  • 157) Wen KW, Wang L, Menke JR, Damania B. Cancers associated with human gammaherpesviruses. FEBS J. 2021

  • 156) Sandhu PK, Damania B. The regulation of KSHV lytic reactivation by viral and cellular factors. Curr Opin Virol. 2021 Dec 3;52:39-47.

  • 155). Carbone A, Borok M, Damania B, Gloghini A, Polizzotto MN, Jayanthan RK, Fajgenbaum DC, Bower M.

    Castleman disease. Nat Rev Dis Primers. 2021. 7(1):84

  • 154) Wong JP, Damania B. SARS-CoV-2 dependence on host pathways. Science. 2021 Feb 26;371(6532):884-885.

  • 153) Chappell DL, White MC, Damania B. Proteomic approaches to investigate gammaherpesvirus biology and associated tumorigenesis. Adv Virus Res. 2021;109:201-254.

  • 152) Alzhanova D, Corcoran K, Bailey AG, Long K, Taft-Benz S, Graham RL, Broussard GS, Heise M, Neumann G, Halfmann P, Kawaoka Y, Baric RS, Damania B, Dittmer DP. Novel modulators of p53-signaling encoded by unknown genes of emerging viruses. PLoS Pathog. 2021 Jan 7;17(1):e1009033.

  • 151) Wang Y, Ma Z, Damania B, Liu P. Protocol for Monitoring DNA-Triggered cGAS/STING Signaling in Mammalian Cells and Mice. STAR Protoc. 2020 Nov 14;1(3):100171. doi: 10.1016/j.xpro.2020.100171.

  • 150) McNamara RP, Caro-Vegas C, Landis JT, Moorad R, Pluta LJ, Eason AB, Thompson C, Bailey A, Villamor FCS, Lange PT, Wong JP, Seltzer T, Seltzer J, Zhou Y, Vahrson W, Juarez A, Meyo JO, Calabre T, Broussard G, Rivera-Soto R, Chappell DL, Baric RS, Damania B, Miller MB, Dittmer DP. High-Density Amplicon Sequencing Identifies Community Spread and Ongoing Evolution of SARS-CoV-2 in the Southern United States. Cell Rep. 2020 Nov 3;33(5):108352.

  • 149) Barzin A, Schmitz JL, Rosin S, Sirpal R, Almond M, Robinette C, Wells S, Hudgens M, Olshan A, Deen S, Krejci P, Quackenbush E, Chronowski K, Cornaby C, Goins J, Butler L, Aucoin J, Boyer K, Faulk J, Alston-Johnson D, Page C, Zhou Y, Fiscus L, Damania B, Dittmer DP, Peden DB. SARS-CoV-2 Seroprevalence among a Southern U.S. Population Indicates Limited Asymptomatic Spread under Physical Distancing Measures. mBio. 2020 Sep 29;11(5):e02426-20.

  • 148) Broussard G, Damania B.Regulation of KSHV Latency and Lytic Reactivation. Viruses. 2020 Sep 17;12(9):E1034.

  • 147) Zhang H, Ni G, Damania B. ADAR1 Facilitates KSHV Lytic Reactivation by Modulating the RLR-Dependent Signaling Pathway. Cell Rep. 2020 Apr 28;31(4):107564.

  • 146) Zhang Y, Ma Z, Wang Y, Boyer J, Ni G, Cheng L, Su S, Zhang Z, Zhu Z, Qian J, Su L, Zhang Q, Damania B, Liu P. Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity. iScience. 2020 Aug 14;23(9):101463.

  • 145) Lange PT, Damania B. Modeling oncogenic herpesvirus infections in humanized mice. Curr Opin Virol. 2020 Aug 9;44:90-96.

  • 144) Ni G, Ma Z, Wong JP, Zhang Z, Cousins E, Major MB, Damania B. PPP6C Negatively Regulates STING-Dependent Innate Immune Responses. mBio. 2020 Aug 4;11(4):e01728-20.

  • 143) Wolf ER, Mabry AR, Damania B, Mayo LD. Mdm2-mediated neddylation of pVHL blocks the induction of antiangiogenic factors. Oncogene. 2020 Jul;39(29):5228-5239.

  • 142) Broussard G, Damania B. KSHV: Immune Modulation and Immunotherapy. Front Immunol. 2020 Feb 7;10:3084.

  • 141) Pluta L, Yousefi B, Damania B, Khan AA. Endosomal TLR-8 Senses microRNA-1294 Resulting in the Production of NFḱB Dependent Cytokines. Front Immunol. 2019 Dec 6;10:2860.

  • 140) Rivera-Soto R, Dissinger NJ, Damania B. Kaposi's Sarcoma-Associated Herpesvirus Viral Interleukin-6 Signaling Upregulates Integrin β3 Levels and Is Dependent on STAT3. J Virol. 2020 Feb 14;94(5):e01384-19.

  • 139) Montgomery ND, Randall C, Painschab M, Seguin R, Kaimila B, Kasonkanji E, Zuze T, Krysiak R, Sanders MK, Elliott A, Miller MB, Kampani C, Chimzimu F, Mulenga M, Damania B, Tomoka T, Fedoriw Y, Dittmer DP, Gopal S. High pretreatment plasma Epstein-Barr virus (EBV) DNA level is a poor prognostic marker in HIV-associated, EBV-negative diffuse large B-cell lymphoma in Malawi. Cancer Med. 2020 Jan;9(2):552-561.

  • 138) Lange P, Damania B. Kaposi Sarcoma-Associated Herpesvirus (KSHV). Trends Microbiol. 2020 Mar;28(3):236-237.

  • 137) Atkins SL, Motaib S, Wiser LC, Hopcraft SE, Hardy PB, Shackelford J, Foote P, Wade AH, Damania B, Pagano JS, Pearce KH, Whitehurst CB. Small molecule screening identifies inhibitors of the Epstein-Barr virus deubiquitinating enzyme, BPLF1. Antiviral Res. 2020 Jan;173:104649.

  • 136) Caro-Vegas C, Sellers S, Host KM, Seltzer J, Landis J, Fischer WA 2nd, Damania B, Dittmer DP. Runaway Kaposi Sarcoma-associated herpesvirus replication correlates with systemic IL-10 levels. Virology. 2020 Jan 2;539:18-25.

  • 135) Park SI, Lin CP, Ren N, Angus SP, Dittmer DP, Foote M, Parton T, Bhatt AP, Fedoriw YD, Roth DP, Cann ML, Johnson GL, Damania B. Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma. Target Oncol. 2019 Oct;14(5):563-575.

  • 134) Wong JP, Stuhlmiller TJ, Giffin LC, Lin C, Bigi R, Zhao J, Zhang W, Bravo Cruz AG, Park SI, Earp HS, Dittmer DP, Frye SV, Wang X, Johnson GL, Damania B. Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma. Proc Natl Acad Sci U S A. 2019 Jul 25. pii: 201903991

  • 133) Rivera-Soto R, Damania B. Modulation of Angiogenic Processes by the Human Gammaherpesviruses, Epstein-Barr Virus and Kaposi's Sarcoma-Associated Herpesvirus. Front Microbiol. 2019 Jul 12;10:1544.

  • 132) Bravo Cruz AG, Damania B.In Vivo Models of Oncoproteins Encoded by Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2019 May 15;93(11).

  • 131) Caro-Vegas C, Bailey A, Bigi R, Damania B, Dittmer DP. Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma. mBio. 2019 Feb 19;10(1).

  • 130) McNamara RP, Chugh PE, Bailey A, Costantini LM, Ma Z, Bigi R, Cheves A, Eason AB, Landis JT, Host KM, Xiong J, Griffith JD, Damania B, Dittmer DP. Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming. PLoS Pathog. 2019 Feb 4;15(2):e1007536

  • 129) Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D. Kaposi sarcoma. Nat Rev Dis Primers. 2019 Jan 31;5(1):9

  • 128) Damania B, Münz C. Immunodeficiencies that predispose to pathologies by human oncogenic γ-herpesviruses. FEMS Microbiol Rev. 2019 Jan 15

  • 127) Dittmer DP, Damania B. Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Associated Disease in the AIDS Patient: An Update. Cancer Treat Res. 2019;177:63-80.

  • 126) McNamara RP, Caro-Vegas CP, Costantini LM, Landis JT, Griffith JD, Damania BA, Dittmer DP. Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles. J Extracell Vesicles. 2018 Nov 30;7(1):1541396.

  • 125) Dittmer DP, Damania B. Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Associated Disease in the AIDS Patient: An Update. Cancer Treat Res. 2019;177:63-80

  • 124) Ma Z, Ni G, Damania B. Innate Sensing of DNA Virus Genomes. Annu Rev Virol. 2018 Sep 29;5(1):341-362.

  • 123) Hopcraft SE, Pattenden SG, James LI, Frye S, Dittmer DP, Damania B. Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency. PLoS Pathog. 2018 Sep 13;14(9):e1007267.

  • 122) Ni G, Ma Z, Damania B. cGAS and STING: At the intersection of DNA and RNA virus-sensing networks. PLoS Pathog. 2018 Aug 16;14(8):e1007148.

  • 121) Hopcraft SE, Moody CA, Damania B. Air-Liquid Interface System To Understand Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma. mSphere. 2018 Jul 18;3(4). pii: e00350-18.

  • 120) Zhang Y, Dittmer DP, Mieczkowski PA, Host KM, Fusco WG, Duncan JA, Damania B. RIG-I Detects Kaposi's Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner. MBio. 2018 Jul 3;9(4).

  • 119) Anders PM, Montgomery ND, Montgomery SA, Bhatt AP, Dittmer DP, Damania B. Human herpesvirus-encoded kinase induces B cell lymphomas in vivo. J Clin Invest. 2018 Jun 1;128(6):2519-2534

  • 118) McNamara RP, Costantini LM, Myers TA, Schouest B, Maness NJ, Griffith JD, Damania BA, MacLean AG, Dittmer DP.Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses. mBio. 2018 Feb 6;9(1)

  • 117) Host KM, Jacobs SR, West JA, Zhang Z, Costantini LM, Stopford CM, Dittmer DP, Damania B. Kaposi's Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes. MBio. 2017 Oct 10;8(5).

  • 116) Ma Z, Hopcraft SE, Yang F, Petrucelli A, Guo H, Ting JP, Dittmer DP, Damania B. NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency. PLoS Pathog. 2017 May 1;13(5):e1006350
    115) Wong JP, Damania B. Modulation of oncogenic signaling networks by Kaposi's sarcoma-associated herpesvirus. Biol Chem. 2017

  • 114) Host KM, Horner MJ, van der Gronde T, Moses A, Phiri S, Dittmer DP, Damania B, Gopal S. Kaposi's sarcoma in Malawi: a continued problem for HIV-positive and HIV-negative individuals. AIDS. 2017 Jan 14;31(2):318-319.

  • 113) Hsia HC, Stopford CM, Zhang Z, Damania B, Baldwin AS. Signal transducer and activator of transcription 3 (Stat3) regulates host defense and protects mice against herpes simplex virus-1 (HSV-1) infection. J Leukoc Biol. 2016.

  • 112) Anders PM, Zhang Z, Bhende PM, Giffin L, Damania B. The KSHV K1 protein modulates AMPK function to enhance cell survival. PLoS Pathogens. 2016. 12(11).

  • 111) Baric, RS, Crosson S, Damania B, Miller, SI, Rubin EJ. Next-Generation High-Throughput Functional Annotation of Microbial Genomes. MBio. 2016. 7(5).

  • 110) Dittmer DP, Damania B. Kaposi sarcoma associated herpesvirus: immunobiology, oncogenesis and therapy. J. Clin. Invest. 2016. 126(9): 3165

  • 109) Eason AB, Sin SH, Lin C, Damania B, Park S, Fedoriw Y, Bacci CE, Dittmer DP. Differential IgM expression distinguishes two types of pediatric Burkitt lymphoma in mouse and human. Oncotarget. 2016.

  • 108) Bhatt AP, Wong JP, Weinberg MS, Host KM, Giffin LC, Buijnink J, van Dijk E, Izumiya Y, Kung HJ, Temple BR, Damania B. A viral kinase mimics S6 kinase to enhance cell proliferation. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7876-81.

  • 107) Zhang Z, Chen W, Sanders MK, Brulois KF, Dittmer DP, Damania B. The K1 Protein of Kaposi's Sarcoma-Associated Herpesvirus Augments Viral Lytic Replication. J Virol. 2016 Aug 12;90(17):7657-66.

  • 106) Johnson AR, Qin Y, Cozzo AJ, Freemerman AJ, Huang MJ, Zhao L, Sampey BP, Milner JJ, Beck MA, Damania B, Rashid N, Galanko JA, Lee DP, Edin ML, Zeldin DC, Fueger PT, Dietz B, Stahl A, Wu Y, Mohlke KL, Makowski L. Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation.
    Mol Metab. 2016 Apr 23;5(7):506-26.

  • 105) Host KM, Damania B. Discovery of a Novel Bat Gammaherpesvirus. mSphere. 2016 Feb 17;1(1).

  • 104) Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. Cell Host Microbe. 2016 Apr 13;19(4):515-28.

  • 103) Dissinger NJ, Damania B. Recent advances in understanding Kaposi's sarcoma-associated herpesvirus. F1000Res. 2016 Apr 25;5. pii: F1000 Faculty Rev-740. doi: 10.12688/f1000research.7612.1.

  • 102) Ma, Z and B. Damania. NLRP3: Immune Activator or Modulator? Journal of Leukocyte Biology. 2016.

  • 101) Ma, Z and Damania, B. The cGAS-STING Defense Pathway and Its Counteraction by Viruses. Cell Host Microbe. 2016. Feb 10; 150-158.

  • 100) Damania, B. A Virological Perspective on Cancer. PLoS Pathog. 2016 Feb 11;12(2):e1005326.

  • 99) Giffin L, West JA, Damania B. Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Modulates Endothelial Cell Movement by Upregulating Cellular Genes Involved in Migration. MBio. 2015 Dec 8;6(6):e01499-15

  • 98) Dittmer DP, Damania B, Sin SH. Animal models of tumorigenic herpesviruses-an update. Curr Opin Virol. 2015;14:145-50.

  • 97) Damania B, Lieberman P. Editorial overview: Viruses and cancer. Curr Opin Virol. 2015.14:viii-x.

  • 96) Jacobs SR, Stopford CM, West JA, Bennett CL, Giffin L, Damania B. KSHV vIRF1 interacts with a member of the Interferon Stimulated Gene 15 pathway. J Virol. 2015 Sep 9. pii: JVI.01482-15.

  • 95) Ma, Z, Jacobs, SR, West, JA, Stopford, C, Zhang, Z, Davis, Z, Barber, GN, Glaunsinger, BA, Dittmer DP, and B. Damania. Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses. Proceedings of the National Academy of Sciences (PNAS). 2015. www.pnas.org/cgi/doi/10.1073/pnas.1503831112

  • 94) Walker, MP, Stopford, CM, Rabinowitz,AR, Goldfarb,G, Yan, F, Fedoriw, Y, Richards, KL, Damania, B, and Major, MB. FOXP1 Activates Wnt Signaling in Diffuse Large B-cell Lymphoma. Science Signaling. 2015. Feb 3;8(362):ra12.

  • 93) Frick A, Fedoriw Y, Richards K, Damania B, Parks B, Suzuki O, Benton CS, Chan E, Thomas RS, Wiltshire T.Immune cell-based screening assay for response to anticancer agents: applications in pharmacogenomics.Pharmgenomics Pers Med. 2015 Feb 26;8:81-98.

  • 92) Sun C, Schattgen SA, Pisitkun P, Jorgensen JP, Hilterbrand AT, Wang LJ, West JA, Hansen K, Horan KA, Jakobsen MR, O'Hare P, Adler H, Sun R, Ploegh HL, Damania B, Upton JW, Fitzgerald KA, Paludan SR. Evasion of Innate Cytosolic DNA Sensing by a Gammaherpesvirus Facilitates Establishment of Latent Infection. J Immunol. 2015. pii: 1402495.

  • 91) Hosseinipour, MC, Sweet, KM, Xiong, J, Namarika,D, Mwafongo, A, Nyirenda, M, Chiwoko,L, Kamwendo, D, Hoffman, I, Lee, J, Phiri, S, Vahrson, W, Damania, B, Dittmer, DP. Viral profiling identifies multiple sub-types of Kaposi sarcoma. mBIO. 5(5):e01633-14.

  • 90) Chugh, P, B. Damania, and D. Dittmer. Toll-like receptor-3 is dispensable for the innate microRNA response to West Nile Virus (WNV). 2014. PLoS One. 9(8):e104770.

  • 89) B. Damania and D. Dittmer. What lies within: Co-infections and Immunity. Cell Host Microbe. 2014. 16(2):145-7.

  • 88) Giffin, L. Yan, F., Major, MB and B. Damania. Modulation of KSHV vIL-6 function by Hypoxia Upregulated Protein 1. J Virol. 2014;88(16):9429-41.

  • 87) Anders, P., Bhende, PM., Foote, M., Dittmer, DP, Park, SI and B. Damania. Dual inhibition of the PI3K/mTOR and MAPK pathways in Non-Hodgkin Lymphoma. Leukemia & Lymphoma. 2014. 1-4.

  • 86) Zhang, L, Mo, J, Seanson, KV, Wen, H, Petrucelli, A, Gregory, SM, Zhang, Z, Schneider, M, Jiang, Y, Fitzgerald, K, Ouyang, S, Liu, ZJ, Damania, B., Shu, HB, Duncan, JA, Ting, JP. . NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING. Immunity. 2014.

  • 85) Giffin L, Damania B. KSHV: pathways to tumorigenesis and persistent infection. Adv Virus Res. 2014;88:111-59.

  • 84) West, JA, Wicks, M, Gregory, SM, Chugh, P, Jacobs, SR, Zhang, Z, Host, KM, Dittmer, DP, and B. Damania. An important role for MAVS in the KSHV lifecycle. J. Virology. 2014.

  • 83) Bentz, GL, Bheda-Magle, A, Wang, L, Shackelford, J, Pagano, JS*, Damania, B*. KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation. Virology. 2014. 448:293-302.

  • 82) Giffin, L. and B. Damania. KSHV: Pathways to Tumorigenesis and Persistent Infection. Advances in Virus Research. 2014. Adv Virus Res. 2014;88:111-59.

  • 81) Hilton IB, Simon JM, Lieb JD, Davis IJ, Damania B, Dittmer DP. The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2013 Nov;87(21):11831-11842.

  • 80) Chugh PE, Sin SH, Ozgur S, Henry DH, Menezes P, Griffith J, Eron JJ, Damania B, Dittmer DP. Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies.PLoS Pathog. 2013 Jul;9(7):e1003484. doi: 10.1371/journal.ppat.1003484

  • 79) Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N.Modulation of B-cell exosome proteins by gamma herpesvirus infection.Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110.

  • 78) Dittmer DP, Damania B.Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update.Curr Opin Virol. 2013 Jun;3(3):238-44. doi: 10.1016/j.coviro.2013.05.012.

  • 77) Yanik EL, Tamburro K, Eron JJ, Damania B, Napravnik S, Dittmer DP.Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011.Infect Agent Cancer. 2013 May 24;8(1):18. doi: 10.1186/1750-9378-8-18.

  • 76) Dillon PJ, Gregory SM, Tamburro K, Sanders MK, Johnson GL, Raab-Traub N, Dittmer DP, Damania B. Tousled-like Kinases Modulate Reactivation of Gammaherpesviruses from Latency.
    Cell Host Microbe. 2013 Feb 13;13(2):204-14. doi: 10.1016/j.chom.2012.12.005.
    -This article was highlighted by F1000 Biology. http://f1000.com/prime/717982020

  • 75) Roy D, Sin SH, Lucas AS, Venkataramanan R, Wang L, Eason A, Chavakula V, Tamburro KM, Hilton IB, Damania B, Dittmer DP. mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis. Cancer Res. 2013 Feb 4.

  • 74) Horan KA, Hansen K, Jakobsen MR, Holm CK, Søby S, Unterholzner L, Thompson M, West JA, Iversen MB, Rasmussen SB, Ellermann-Eriksen S, Kurt-Jones E, Landolfo S, Damania B, Melchjorsen J, Bowie AG, Fitzgerald KA, Paludan SR. Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors.J. Immunol. 2013 Mar 1;190(5):2311-9. doi: 10.4049/jimmunol.1202749.

  • 73) Bhatt AP, Damania B. AKTivation of PI3K/AKT/mTOR signaling pathway by KSHV. Front Immunol. 2012;3:401. doi: 10.3389/fimmu.2012.00401. Epub 2013 Jan 7.

  • 72) Chen W, Sin SH, Wen KW, Damania B, Dittmer DP. Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins.
    PLoS Pathog. 2012 Nov;8(11):e1003048. doi: 10.1371/journal.ppat.1003048.

  • 71) Jacobs SR, Gregory SM, West JA, Wollish AC, Bennett CL, Blackbourn DJ, Heise MT, Damania B. The viral interferon regulatory factors of kaposi's sarcoma-associated herpesvirus differ in their inhibition of interferon activation mediated by toll-like receptor 3.
    J Virol. 2013 Jan;87(2):798-806. doi: 10.1128/JVI.01851-12. Epub 2012 Oct 31.
    -J. Virology Spotlight Feature article

  • 70) West JA, Gregory SM, Damania B.Toll-like receptor sensing of human herpesvirus infection. Front Cell Infect Microbiol. 2012;2:122. doi: 10.3389/fcimb.2012.00122.

  • 69) Tamburro KM, Yang D, Poisson J, Fedoriw Y, Roy D, Lucas A, Sin SH, Malouf N, Moylan V, Damania B, Moll S, van der Horst C, Dittmer DP. Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A.Virology. 2012 Nov 10;433(1):220-5. doi: 10.1016/j.virol.2012.08.014.

  • 68) Bhatt, AP., Jacobs, SR., Freemerman, AJ, Makowski L, Rathmell, JC, Dittmer, DP, and B. Damania. Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma. 2012. Proceedings of the National Academy of Sciences (PNAS). Jul 17;109(29):11818-23.

  • 67) Damania B, Blackbourn DJ. Innate barriers to viral infection. Future Microbiol. 2012 Jul;7:815-22.

  • 66) Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP. The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy.Immunity. 2012. 36(6):933-46.

  • 65) Jacobs SR, Damania B. NLRs, inflammasomes, and viral infection. J Leukoc Biol. 2012 May 10.

  • 64) Dittmer DP, Richards KL, Damania B. Treatment of kaposi sarcoma-associated herpesvirus-associated cancers. Front Microbiol. 2012;3:141. Epub 2012 Apr 18.

  • 63) Dittmer DP, Bhatt AP, Damania B.Rapalogs in viral cancers. Expert Opin Investig Drugs. 2012 Feb;21(2):135-8.

  • 62) Gregory SM, Wang L, West JA, Dittmer DP, Damania B. Latent Kaposi's sarcoma-associated herpesvirus infection of monocytes downregulates expression of adaptive immune response costimulatory receptors and proinflammatory cytokines.
    J Virol. 2012 Apr;86(7):3916-23. Epub 2012 Jan 25.

  • 61) Dittmer DP, Bhatt AP, Damania B.Rapalogs in viral cancers. Expert Opin Investig Drugs. 2012 Feb;21(2):135-8. Epub 2012 Jan 4.

  • 60) Gregory SM, Damania B. Inhibition of the inflammasome response by a viral protein that interacts with NLRs. Commun Integr Biol. 2011 Jul;4(4):416-8.

  • 59) Guilluy C, Zhang Z, Bhende PM, Sharek L, Wang L, Burridge K, Damania B. Latent KSHV infection increases the vascular permeability of human endothelial cells. Blood. 2011 Aug 31.

  • 58) Roy D, Sin SH, Damania B, Dittmer DP. Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines. Blood. 2011 Aug 18;118(7):e32-9.

  • 57) Gregory,SM, Davis,BK., West, JA., Taxman, D., Matsuzawa, S., Reed, J., Ting. JP, and B. Damania. Discovery of a Viral NLR Homolog that Inhibits the Inflammasome. Science. 2011.
    This article was featured in:
    -Da Silva, K. Editors’ Choice: Evasion through evolution. Nature Medicine 2011
    -Sanchez, C. Research Highlight: Viral immune evasion: NLR identity theft. Nature Reviews Microbiology 2011
    -Dempsey, L. Research Highlight: Viral inflammasome inhibitor. Nature Immunology 2011.
    -Mueller, K. Editors’ Choice: Immune Evasion tactic. Science Signaling. 2011
    -F1000 Biology (F1000.com/8136972) and (F1000.com/8136972)

  • 56) Ozgur S, Damania B, Griffith J. The Kaposi's sarcoma-associated herpesvirus ORF6 DNA binding protein forms long DNA-free helical protein filaments. J Struct Biol. 2011

  • 55) West JA, Gregory SM, Sivaraman V, Su L, Damania B. Activation of Plasmacytoid Dendritic Cells by Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2011. 85(2):895-904.

  • 54) Bhende PM, Park SI, Lim MS, Dittmer DP, Damania B. The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma. Leukemia. 2010. 24(10):1781-4.

  • 53) Moyo TK, Richards KL, Damania B. Use of cidofovir for the treatment of HIV-negative human herpes virus-8-associated primary effusion lymphoma. Clin Adv Hematol Oncol. 2010. (5):372-4.

  • 52) Bhatt, AP, Bhende, PM, Sin, SH, Roy, D, Dittmer, DP and B. Damania. Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas. Blood. 2010. 115(22):4455-63.

  • 51) Wen, K and B. Damania. HSP90 and HSP40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1. Oncogene. 2010. 29(24):3532-44.

  • 50) West JA, Damania B. Kaposi's sarcoma-associated herpesvirus and innate immunity.Future Virol. 2010 Mar 1;5(2):185-196.

  • 49) Gregory SM, Damania B. KSHV and the toll of innate immune activation. Cell Cycle. 2009 Oct 15;8(20):3246-7.

  • 48) González CM, Wang L, Damania B. KSHV Encodes a Viral Deubiquitinase. J Virol. 2009 Oct;83(19):10224-33.

  • 47) Wen KW, Damania B. Kaposi sarcoma-associated herpesvirus (KSHV): Molecular biology and oncogenesis. Cancer Lett. 2009.

  • 46) Wen, KW, Dittmer, DP and B. Damania. Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus. J Virol. 2009 Oct;83(19):9786-802.

  • 45) Gregory SM, West JA, Dillon PJ, Hilscher C, Dittmer DP, Damania B. Toll-like receptor signaling controls reactivation of KSHV from latency. Proc Natl Acad Sci U S A. 2009 Jun 29.
    This article was highlighted in Science Signaling: L. Bryan Ray. For Whom the Toll-Like Receptor Signals. Sci. Signal.,Vol. 2, Issue 80, p. ec242

  • 44) O'Hara AJ, Chugh P, Wang L, Netto EM, Luz E, Harrington WJ, Dezube BJ, Damania B, Dittmer DP. Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma. PLoS Pathog. 2009 Apr;5(4). Website: http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000389

  • 43) O'Hara AJ, Wang L, Dezube BJ, Harrington WJ Jr, Damania B, Dittmer DP. Tumor suppressor micro RNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma. Blood. 2009 Feb 27.

  • 42) Wang, L. and B. Damania. KSHV confers a cell survival advantage to endothelial cells. Cancer Research. 2008. 68(12):4640-8.
    This article was highlighted in Nature Reviews Cancer: Angiogenesis: Survival of the Infected. Vol.8, page 569 (August 2008).
    This article was also featured in the August 2008 Signaling Gateway Highlights section: http://www.signaling-gateway.org/update/updates/200808/index.html

  • 41) Tomlinson, CC and B. Damania.A critical role for endocytosis in the regulation of signaling by the KSHV K1 protein. J. Virology. 2008. 82(13):6514-23.

  • 40) West, J. and B. Damania. Upregulation of the TLR3 pathway by Kaposi's sarcoma-associated herpesvirus during primary infection. J. Virology. 2008. 82(11):5440-9.

  • 39) Nun, T.K., Kroll D.J.,Oberlies,N.H., Soejarto, DD, Case, RJ, Piskaut, P.,Matainaho, T., Hilscher, C., Wang, L., Dittmer, DP., Gao, SJ and B. Damania. Development of a Novel, High Throughput Assay to Screen Anti-Viral Drugs against Kaposi’s Sarcoma-Associated Herpesvirus. Molecular Cancer Therapeutics. 2007. Aug;6(8):2360-70.

  • 38) Mark, L. Spiller, Okroj, Chanas, Aitken, Wong,S., Damania,B., Blom,H and D. Blackbourn. Molecular characterization of the Rhesus Rhadinovirus (RRV) ORF4 gene and the RRV complement control protein (RCP) it encodes. J Virol. 2007 Apr;81(8):4166-76.

  • 37) Hoon-Sin,S., Roy,D., Wang,L., Staudt M.R., Fakhari,FD., Patel,DD. Koon,H., Damania, B. and D.P. Dittmer. Rapamycin is efficacious against primary effusion lymphoma (PEL). Blood. 2007 Mar 1;109(5):2165-73.

  • 36) Damania B. DNA tumor viruses and human cancer. Trends in Microbiology. 2007.

  • 35) Wang, L., Dittmer, D. P., Tomlinson, C.C., Fakhari, F.D. and B. Damania. “Immortalization of primary endothelial cells by the K1 protein of Kaposi’s sarcoma-associated herpesvirus (KSHV). 2006. Cancer Research. 66(7):3658-66.

  • 34) Bowser, B.S., Song, M.J., Sun, R., Morris, S. and B. Damania. “Identification of Multiple Rta Responsive Elements in the KSHV K1 promoter.” 2006. Virology. 348(2):309-27.

  • 33) Gonzalez, C.M., Wong, E.L., Bowser, B.S., Hong, G, Kenney S. and B. Damania. Identification and Characterization of the KSHV Orf49 Protein. 2006. J. Virology. 80(6):3062-70.

  • 32) Wong, E.L. and B. Damania. Transcriptional Regulation of the Kaposi’s Sarcoma-Associated Herpesvirus K15 Gene. 2006. J. Virology;80 1385-1392.

  • 31) Bilelo, J., Morgan, J. Damania, B., Lang, S, and RC Desrosiers. A Genetic System for Rhesus Monkey Rhadinovirus: Use of Recombinant Virus to Quantitate Antibody-Mediated Neutralization. 2006. J. Virology;80 1549-1562.

  • 30) Hong, G., Kumar, P., Wang, L., Damania, B., Gulley, M.L., Delecluse H-J., Polverini, P., and S. Kenney. Epstein-Barr Virus Lytic Infection is Required for Efficient Production of the Angiogenesis Factor VEGF in Lymphoblastoid Cell Lines. J Virol. 2005 79(22):13984-92.

  • 29) Wong, E.L. and B. Damania. Linking KSHV to Human Cancer.2005. Current Oncology Reports (5):349-356.

  • 28) Dittmer, D.P., Gonzalez C.M., Vahrson, W., DeWire, S.M., and B. Damania. “Whole-Genome Transcription Profiling of Rhesus Monkey Rhadinovirus.” 2005. Journal of Virology 79: 8637-8650.

  • 27) Cai, W., Lu, S., Zhang, Z., Gonzalez, C.M., Damania B., and B. Cullen. Kaposi’s sarcoma associated herpesvirus expresses an array of novel viral microRNAs in latently infected cells. 2005. Proc. Natl. Acad. Sciences. 2005. 102(15):5570-5.

  • 26) DeWire, S. and B. Damania. “The Latency-Associated Nuclear Antigen of Rhesus Monkey Rhadinovirus (RRV) Inhibits Viral Replication through Repression of Orf50/Rta Transcriptional Activation.” J. Virol. 2005. 79; 3127-3138.

  • 25) Payton ME, d'Offay JM, Prado ME, Black DH, Damania B, White GL, Eberle R. Comparative transmission of multiple herpesviruses and simian virus 40 in a baboon breeding colony. Comp Med. 2004. 54(6):695-704.

  • 24) Pagano, J.S. Blaser, M. Buendia, M.A., Damania, B., Khalili, K. Raab-Traub, N., Roizman, B. Validation Of A Causal Relationship: Criteria To Establish Etiology of Viral Cancers. Seminars in Cancer Biology. Semin Cancer Biol. 2004. 14(6):453-71.

  • 23) Damania, B. Oncogenic Gammaherpesviruses: Comparison of Viral Proteins involved in Tumorigenesis. Nature Reviews Microbiology, 2004. Vol. 2, pp.656-668.

  • 22) Damania, B. Modulation of cell signaling pathways by Kaposi’s Sarcoma-Associated Herpesvirus (KSHV/HHV-8). Cell Biochemistry & Biophysics, 2004.Vol. 40, pp. 305-322

  • 21) Wang, L., Wakisaka N., Tomlinson, C., DeWire S., Krall, S., Pagano, J. and B. Damania. "The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV/HHV8) K1 Protein Induces Expression of Angiogenic and Invasion Factors." Cancer Research.2004. 64. pp.2774-2781.

  • 20) Damania B., J. H. Jeong, B. S. Bowser, S. M. DeWire and D. P. Dittmer. “A Functional Comparison of Rta Transactivator Proteins of Gamma-2 Herpesviruses.” J.Virol. 2004. 78. p.5491-5499.

  • 19) Tomlinson, C.C., and B. Damania. The K1 Protein of Kaposi’s Sarcoma-Associated Herpesvirus Activates the Akt Signaling Pathway. J. Virol. 2004. 78 (4): 1918-27.

  • 18) O’Connor, C., Damania, B. and Kedes, D.H. Capsid. De Novo Infection with Rhesus Monkey Rhadinovirus Leads to the Accumulation of Multiple Intranuclear Capsid Species during Lytic Replication but Favors the Release of Genome-Containing Virions. J Virol. 2003 Dec 15;77(24):13439-13447.

  • 17) Yu, X.K., O’Connor, C., Atanosov, I., Damania, B., Kedes, D., and Z.H. Zhou. Three-Dimensional Structures of the A, B, and C Capsids of Rhesus Monkey Rhadinovirus: Insights into Gammaherpesvirus Capsid Assembly, Maturation, and DNA Packaging. J Virol. 2003 Dec 15;77(24):13182-13193.

  • 16) DeWire, S.M., Money, E.S., Krall, S.P., and B. Damania. Rhesus Monkey Rhadinovirus (RRV): Construction of a RRV-GFP Recombinant Virus and the Development of Assays to Assess Viral Replication. 2003. Virology. 312 (1): 122-134.

  • 15) Bowser, B.S., DeWire, S. and B. Damania. Transcriptional Regulation of the KSHV K1 viral gene of Kaposi’s sarcoma-associated herpesvirus. 2002.Journal of Virology, 76 (24): 12574-12583.

  • 14) DeWire, S., McVoy,, M., and B. Damania. Kinetics of Expression of Rhesus Monkey Rhadinovirus (RRV) and the Identification and Characterization of a polycistronic transcript encoding the RRV Orf 50/Rta, RRV R8 and R8.1 genes. 2002.Journal of Virology, 76(19): 9819-9831.

  • 13) Damania, B. and R.C. Desrosiers. Oncogenic gamma-herpesviruses. Philosophical Transactions of the Royal Society.2001.

  • 12) Choi JK, Means R, Damania B., and J.U. Jung. Molecular piracy of Kaposi’s sarcoma associated herpesvirus.2001. Cytokine and Growth Factor Rev. 12(2-3):245-257.

  • 11) Damania, B and J.U. Jung. Comparative analysis of the transforming mechanisms of Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, and Herpesvirus saimiri. 2000. Advances in Cancer Research, 80:51-82.

  • 10) Li, M., Damania, B. Alvarez, X., Ogryko, G., Ozato, K., and J.U. Jung. The Kaposi sarcoma herpesvirus vIRF gene inhibits histone acetyltransferases. Molecular & Cellular Biology. 20(21):8254-63. 2000.

  • 9) Lee, B.S., Damania, B., and J.U. Jung. The Kaposi's sarcoma-associated herpesvirus K1 and Rhesus Monkey Rhadinovirus R1 proteins. EBV Report. 1999. Vol. 6 (5), pp. 123-125.

  • 8) Alexander, L., Denekamp, L., Auerbach, M., Knappe, A., Damania, B. and R.C. Desrosiers. Sequence analysis of Rhesus Rhadinovirus Isolate H26-95.Journal of Virology, 2000 76 (8).

  • 7) Damania, B. DeMaria, M., Jung, J.U. and R.C. Desrosiers Activation of lymphocyte signaling by the R1 protein of Rhesus monkey rhadinovirus.Journal of Virology, 2000 (76)6.

  • 6) Damania, B., Choi, J.K. and Jung J.U. Gammaherpesviruses: Transforming functions of the first open reading frames. J. Virol. 1999.Journal of Virology, 2000. 76 (4).

  • 5) Damania, B. Lee, H. and Jung, J.U. Primate herpesviral oncogenes. Mol. Cells, 1999. Vol. 9 (4), pp. 20-24.

  • 4) Damania B, Li M, Choi JK, Alexander L, Jung JU, Desrosiers RC. Identification and characterization of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeys. J. Virol., 1999. Vol. 73(6), pp. 5123-5133.

  • 3) Damania B, Lieberman P, Alwine JC. Simian virus 40 large T antigen stabilizes the TATA-binding protein-TFIIA complex on the TATA element. Mol Cell Biol. 1998 Jul;18(7):3926-35.

  • 2) Damania B, Mital R, Alwine JC. Simian virus 40 large T antigen interacts with human TFIIB-related factor and small nuclear RNA-activating protein complex for transcriptional activation of TATA-containing polymerase III promoters. Mol Cell Biol. 1998 Mar;18(3):1331-8.

  • 1) Damania B, Alwine JC. TAF-like function of SV40 large T antigen. Genes Dev. 1996 Jun 1;10(11):1369-81.

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